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Tom Cheney of the Washington Senators holds the MLB record for most strikeouts in a single game when he struckout 21 Baltimore Orioles batters in a 16 inning game in 1962. Kerry Wood, Randy Johnson, and Roger Clemens (twice) hold the MLB record for most strikeouts in a 9 inning game with 20. == ==

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โˆ™ 2008-09-16 15:08:31
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Q: What pitcher holds the MLB record for most strikeouts in a game?
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