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Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.

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Q: What left handed pitcher holds the record for the most career strikeouts?
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What pitcher has the most strikeouts in magor league baseball?

Nolan Ryan holds the career record with 5,714 strikeouts.


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Tom Cheney of the Washington Senators holds the MLB record for most strikeouts in a single game when he struckout 21 Baltimore Orioles batters in a 16 inning game in 1962. Kerry Wood, Randy Johnson, and Roger Clemens (twice) hold the MLB record for most strikeouts in a 9 inning game with 20. == ==


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Hall of Fame pitcher Walter Johnson retired in 1927 with 3,508 career strikeouts, the MLB record. Ryan broke that record in 1983 and went on to strikeout a total of 5,714 batter during his career, a record that will be around for a long time.


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