Pitchers are chosen by the manager of the team
There are different amount of pitchers in a 40-man roster, whether you have 25 pitchers (in both the starting rotation and the bullpen) or just have 10, in any game, you can use all of your pitchers. However, you can't use a pitcher once they are taken out of the game.
There are 30 teams in MLB and each team carries 11 or 12 pitchers. That would make between 330-360 pitchers on active rosters in MLB.
Two. One for each team.
Denny mclaine, then who else ?
Ken Holtzman (Oakland) and Gary Nolan (Cincinnati)
Weaver(angels) Weaver(dodgers) beckett(boston)
Through games played on 9/13/10, the two MLB pitchers with the most wins in their 40s are Phil Niekro with 121 and Jamie Moyer with 103.
In MLB, 21 by Tom Cheney of the Washington Senators in a 16 inning complete game, 2-1 victory, against the Baltimore Orioles on September 12, 1962. Cheney's 21 strikeouts is an MLB record for strikeouts in a game by a pitcher. Several MLB pitchers have struckout 20 batters in a game (all of which were 9 inning games) but no MLB pitcher has struckout more batters in a game than Cheney. For the record, Cheney had 13 strikeouts through 9 innings.
There are very few sidearm submarine pitchers in the MLB but to name a few there is Mike Myers, Cla Meredith, Chad Bradford, and Mike Koplove.
Paul Derringer of the Reds and Joe Bowman of the Phillies on May 24, 1935.
The MLB All-Stars are picked by the fans, and the pitchers are picked by MLB. The players in the all-star game must be all-around great players, EXP: Oakland's Jemile Weeks.
He was one of the best pitchers in MLB history.
Randy Johnson is a retired MLB Pitcher. With 4 Cy Young awards, A World Series MVP and Victory, a perfect game, and a no-hitter, he is one of the most decorated pitchers to ever play.