George Mason 2006 LSU 1986
yes
Michigan State is the number 2 seed.
Since the 64 team structure, Virginia made it to the final 4 in 1984 as a number 7 seed.
Yes 2011
In 1985 Villanova won a national championship as an 8 seed beating Georgetown the highest seed ever to win a national championship
There have been three times in NCAA Men's Basketball history that no #1 seed has been in the Final Four. The only three years were 1980, 2006, and 2011 with the following teams included in their separate final fours: 1980: Louisville (#2 seed), Iowa (#5 seed), Purdue (#6 seed), and UCLA (#8 seed) 2006: UCLA (#2 seed), Florida (#3 seed), LSU (#4 seed), and George Mason (#11 seed) 2011: Butler (#8 seed), UConn (#3 seed), VCU (#11 seed), and Kentucky (#4 seed)
2011 is the first time
11
This has never happened. In 2006 and 1980 there were no number 1 seeds, but both years there was one number 2 seed remaining. 2011 was the first year that there was no number 1 or number 2 seeds that made the final four.
A 16 seed has never defeated a 1 seed, which is their first opponent of the round of 64
the (4) seed Arizona Wildcats in 1997, Defeated (1) seed Kansas Jayhawks (favored to win it all) in the sweet sixteen: final score 85-82 Defeated (1) seed North Carolina Tar Heels in the final four: final score 66-58 Defeated (1) seed Kentucky Wildcats in the National Championship: final score 84-79