Brett FarveFavre retired following the 2010 season. Going into the 2012 season, Peyton Manning is the active leader for most interceptions thrown, with 198.
In 2010 Peyton Manning through 6 interceptions against the Titans
Brett Favre has more career touchdown passes and more career interceptions thrown than Peyton Manning
Through the 2012 season, Peyton Manning has thrown 436touchdowns in his career.
He threw 3 interceptions to Antonio Cromartie when he played for the San Diego Chargers.
He has never trown 50 touchdowns. Tom brady has thrown 50, but Peyton manning has only thrown 49 in one season.
For the 2010 regular season, that was Eli Manning of the New York Giants with 25.