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Yes--there's no limit to how many players can be substituted at once. Also, in the National League (or any league where pitchers have to bat) a team can make a "double switch", which in the case of a pitcher and catcher would result in the new pitcher batting in the previous catcher's spot in the batting order, and the new catcher in the pitcher's spot (probably ninth).

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13y ago
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14y ago

The starting pitcher and any substitute must pitcher to a minimum of one batter, or have an Out made, before he can be replaced. Other than that, the Manager can change the pitcher whenever he wants to.

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10y ago

Teams in the Major Leagues can change pitchers as much as they want to in a game but any pitcher that comes in is required to face a minimum of one batter before they can be taken out of the game for a new Pitcher.

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15y ago

Inning---but not during an at bat. Although ambidextrous pitchers are extremely rare.

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12y ago

Any time.

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Q: How many times can a team change pitchers in a game?
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