With all medicines it is best to check with your health care professional (GP, pharmacist etc) whether it is safe to dive on.
Having done a quick check on the internet for the side effects of Topomax it doesn't appear to have any physiological effects which may impede diving BUT it does mention effects on concentration and diving which may make diving unsafe.
For this reason, please check with your health care professional to see if any symptoms you have may affect your diving. Depending what country you live in, you may find it easier to pop in to a pharmacist and ask them rather than making a doctor's appointment. Either way it is always best to understand the effects of medication fully before you undertake activities such as diving.
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