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There is no best defence against that movement.
There are dozens of openings that start with that movement
Is the most common first movement in Chess and there are lots of answers to it, chek this link:
http://www.chessgames.com/perl/explorer?node=21720&move=1.5&moves=e4&nodes=21720
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Earn +20 ptsQ: What is the best defence against e4 in chess?
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