There is no best defence against that movement.
There are dozens of openings that start with that movement
Is the most common first movement in Chess and there are lots of answers to it, chek this link:
http://www.chessgames.com/perl/explorer?node=21720&move=1.5&moves=e4&nodes=21720
e4 is three spaces in front of white's king .
1.e4 c5
In chess, the opening move e4 is generally considered better than d4 because it controls the center of the board and allows for quicker development of pieces.
The best response to the moves 1. e4 e5 2. Nf3 Qf6 in a game of chess is to continue developing your pieces with 3. Bc4. This move puts pressure on Black's weak f7 square and helps control the center of the board.
Common responses to the e4 opening move in chess include e5, c5, and c6. These moves aim to control the center of the board and develop pieces quickly.
1.e4 e5 2.Ne2
The common opening moves in chess that involve the keywords e4 and Nf3 are part of the King's Pawn Opening. These moves are aimed at controlling the center of the board and developing the knight to a strong position.
In chess notation, E4 refers to the opening move where the pawn in front of the king moves two squares forward. In the context of someone dying, E4 does not have a specific meaning. It is important to consider the context in which E4 is being used to determine its significance.
In the opening sequence involving the moves e4, d5, and Nc3 in chess, common moves include the Scandinavian Defense, where Black plays d5 in response to White's e4, and White follows up with Nc3 to develop a knight and put pressure on Black's pawn on d5.
The center of a chess board are the d4, e4, d5 and e5 squares. These are the most important squares to have control over in most openings and during the game.
It's a matter of personal opinion. Popular choices include: e5 (open), e6 (french), c5 (sicilian), and c6 (caro-kann).
Common opening moves in chess that involve the moves e4, e5, and f3 include the King's Gambit, the Vienna Game, and the Bishop's Opening. These openings aim to control the center of the board and develop pieces quickly.