That was George Blanda of the Houston Oilers who threw 42 interceptions in 1962. Second highest is Vinny Testeverde of the Tampa Bay Buccaneers who threw 35 interceptions in 1988.
In 2006 Ben Roethlisberger threw a career high 23 interceptions.
2004 - 11 INT's, 2005 - 9 INT's, 2006 - 23 INT's, 2007 - 11 INT's, 2008 - 15 INT's, 2009 - 12 INT's.
Through the 2008 season in the NFL, that is Brett Favre with 310 career interceptions.
michael jordan
Unknown, as the 2010 NFL season has not begun yet.
In 2010, Eli Manning of the New York Giants threw the most interceptions with 25.
Dan Fouts. Fouts threw 242 career INTs, 12th most overall through the 2010 season, and never led the NFL in interceptions for a season. The closest he came was 1979 when he threw 24 INTs and the NFL leader was Brian Sipe with 26.
Brett farve for a fact has thrown the most touchdowns. But I'm not sure if he threw the most interceptions as well
11 in 1975. He led the NFL in interceptions that season.
Bret favre
Jim hardy of the cardinals threw 8 interceptions in a game in the 1950's
Peyton Manning
In the NFL, the record for interceptions in a season is 14 by Dick 'Night Train' Lane of the Los Angeles Rams in 1952.
The QBs that threw the most INTs were Jon Kitna, Carson Palmer, and Eli Manning with 20 apiece. The DB with the most INTs was Antonio Cromartie with 10.