George Gipp wore the number 66 while he played at Notre Dame.
Paul Hornung
Joe Montana wore #3 during his time at Note Dame. He attended Notre Dame from 1974 to 1978.
Tyler
Brady Quinn wore 10 at Notre Dame when he was quarterback there.
Tom gate wood
Julian
paul hornung
Jerome Bettis did not claim a major in college. He did attend college at Notre Dame but did not graduate. He took classes in history, philosophy, marketing and business.
The most famous was Tony Rice a Quarterback in 1988 for the national championship team.
Assuming you're asking about the football team, two players wore #5 in 2010: Armando Allen (RB) on offense, and Manti Te'o (MLB) on defense.
Marc Edwards (Fullback)Grant Irons (Defensive End)