On average, the defensive ends (DE) are the lightest linemen. They need speed more than mass. That applies to both college and the pros. You will get an occasional DE that weighs a lot more than average. They are usually on 3-4 defensive schemes. These guys don't really meet the definition of defensive end, as the outside linebacker (OLB) performs their function (outside contain).
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The lightest NFL player is on the Giants he weighs 160lbs and is 5'10'' and plays DB.
His name is Lamont Brightful. He has played in games so he is an offical NFL player.