NL - Albert Pujols - 42
AL - Jose Bautista - 54
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As of July 23, 2014, Joe Abreu is leading the AL with 29 home runs, and Anthony Rizzo is leading the NL with 25.
In 2009 Albert Pujols led the National League with 47 home runs. Carlos Pena, and Mark Teixeira led the Amercan League with 39.