As of the 2008 season, in the NFL the most passing yards in a single season is 5,084 by Dan Marino of the Miami Dolphins in 1984.
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Brett Farve has the most career passing yards in NFL history with 69,369 yards over 19 seasons. The closest active NFL player is Peyton Manning with 50,128 yards over 12 seasons.
Brett Favre has the most passing yards in the NFL.He has 71775 and last season had six 300 and over passing yard games.