Brett Favre's last NFL career touchdown pass was a 12 yard pass to Donald Lee. It came with 5:00 minutes to play in the 3rd quarter of the 2007 NFC Championship game against the NY Giants in Green Bay, WI.
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Well, this can be answered two ways considering Favre's "last pass" as a Green Bay Packer was an interception in overtime of the 2008 NFC Championship game... With that said, the Packer (or teammate) that caught Favre's last pass was... Donald Lee. However, Favre's very "last pass" as a Packer was intercepted by Corey Webster from the Giants.
Brett Favre's last completion as a Jet was a 4 yard pass to Leon Washington.
Source:http://www.nfl.com/gamecenter/2008122809/2008/REG17/dolphins@jets/analyze/box-score#analyze-channels:cat-post-playbyplay
Randy Moss.
Favre's final TD pass at Lambeau came when he was playing with the Minnesota Vikings. He threw a 4 yard TD pass to Moss in the 3rd quarter of the game played October 24, 2010.
He threw his last touchdown to Sidney Rice on January 24, 2010 in the Conference Championship (Minnesota Vikings at New Orleans Saints).