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According to www.Missouri.edu, no one is sure about the origin of the nickname Mizzou. The first known use of the word was in the Missouri Alumni Quarterly in 1906. According to facultycouncil.missouri.edu, one of the names that the University of Missouri was known as in the early 1900s was Missouri State University. Pronouncing the initials (MSU) would sound like mi-zoo.

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Q: Where did the name mizzou come from?
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