Michigan defeated USC by a score of 22-14 on January 2, 1989 during the 1989 Rose Bowl Game.
Satorday Saturday, November 13 @ Purdue
Not historically. Michigan is the winningest college football program of all-time. But don't let that fool you. Any school could have that title had they been playing football since the 1800's. As of right now, though, State has won the last 2 matches over Michigan and has attended bowl games, while Michigan sat at home.
Florida in 2009
once
2002-2007.
1965-1967.
34
Michigan, 27-7, on September 2, 2006.
Prior to the 2010 season, that was 1999 when they lost to Florida State in the last game of the regular season, Alabama in the SEC Championship Game, and Michigan State in the Florida Citrus Bowl.
1959-1962
Prior to the 2008 season, that was November 6, 2007 when Central Michigan defeated Western Michigan 34-31.