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  1. Take the Massachusets Turnpike WEST along I-90 to the New York State Thruway towards NEW YORK and BUFFALO in New York.
  2. The thruway will then become I-90. Continue WEST on I-90 through New York and Pennsylvania to I-270 SOUTH - EXPRESS LANES towards COLUMBUS at EXIT 190 in Ohio.
  3. Take I-271 SOUTH - EXPRESS LANES to I-480 WEST to TOLEDO.
  4. Take I-480 WEST TO I-80 OHIO TURNPIKE towards TOLEDO which is a TOLL ROAD.
  5. Take I-80 WEST along the Ohio Turnpike to US-20 TO I-475/US 23 at EXIT 59 off the turnpike.
  6. Once you are past the toll boots, stay right and then follow signs to I-475/US-23.
  7. Once you are at JCT I-475/US 23. Look for signs to I-475/US-23 NORTH to ANN ARBOR.
  8. When US-23 splits off of I-475, stay to the left and go onto US-23 NORTH to ANN ARBOR.
  9. Take US-23 NORTH to ANN ARBOR.
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Q: What is the best driving route from Boston MA to Ann Arbor Michigan?
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