Here's the all-time list as of the start of the 2008 season:
Chicago WHITESOX
CAREER
RBI RBI
1 Frank Thomas 1465
2 Luke Appling 1116
3 Harold Baines 981
4 Paul Konerko 866
5 Minnie Minoso 808
6 Eddie Collins 804
7 Carlton Fisk 762
8 Robin Ventura 741
9 Nellie Fox 740
10 Magglio Ordonez 703
11 Sherm Lollar 631
12 Bibb Falk 627
13 Ray Schalk 594
14 Willie Kamm 587
15 Earl Sheely 582
16 Ozzie Guillen 565
17 Carlos Lee 552
18 Shano Collins 541
19 Bill Melton 535
20 Ray Durham 484
21 Carlos May 479
22 Luis Aparicio 464
23 Jorge Orta 456
24 Frank Isbell 447
25 Happy Felsch 446
26 Greg Walker 442
27 Zeke Bonura 440
28 Joe Jackson 426
29 Buck Weaver 420
30 Pete Ward 407
31 Floyd Robinson 400
32 Taffy Wright 399
33 Jim Landis 398
34 Mike Kreevich 386
35 Jackie Hayes 384
T36 Joe Kuhel 382
T36 Jim Rivera 382
38 Jose Valentin 379
39 George Davis 377
40 Johnny Mostil 376
41 Fielder Jones 375
42 Ron Kittle 374
43 Rip Radcliff 368
44 Joe Crede 367
45 Al Smith 360
46 Chet Lemon 348
47 Lee Tannehill 346
48 Lamar Johnson 343
49 Ron Karkovice 335
50 Lance Johnson 327
51 Billy Sullivan 325
52 Harry Hooper 320
T53 Cass Michaels 317
T53 Greg Luzinski 317
T55 Jimmy Dykes 307
T55 Chico Carrasquel 307
57 Al Simmons 302
58 Nixey Callahan 298
59 Mike Tresh 296
60 Eddie Robinson 294
61 Carl Reynolds 291
62 Bill Barrett 289
63 Dave Philley 286
T64 Jermaine Dye 284
T64 Juan Uribe 284
T64 Ivan Calderon 284
67 Tom McCraw 283
68 Ron Hansen 282
69 Dan Pasqua 278
70 Tim Raines 277
71 Jiggs Donahue 273
72 Albert Belle 268
73 Patsy Dougherty 261
74 Bob Kennedy 259
T75 Ping Bodie 246
T75 Don Kolloway 246
77 Dick Allen 242
78 Ed Herrmann 237
79 Danny Green 230
80 Luke Sewell 228
T81 Bill Cissell 221
T81 Ken Berry 221
83 Aaron Rowand 211
84 Jim Thome 205
85 Scott Fletcher 202
86 Jerry Hairston 199
87 Gee Walker 198
88 Wally Moses 197
89 Chick Gandil 193
T90 Larry Doby 190
T90 Jack Fournier 190
T90 Pat Kelly 190
93 Walt Dropo 188
94 Roy Sievers 185
95 Ralph Hodgin 184
96 Ken Henderson 180
T97 Chris Singleton 179
T97 Wayne Nordhagen 179
99 Sam Mertes 177
100 George Bell 176
T101 Bud Clancy 175
T101 Swede Risberg 175
103 Mule Haas 174
T104 Alex Metzler 170
T104 Harry Lord 170
T104 A.J. Pierzynski 170
107 Tadahito Iguchi 169
108 Eric Soderholm 168
109 Don Buford 166
110 Bucky Dent 165
111 Larry Rosenthal 161
112 Buck Crouse 160
113 Ralph Garr 158
114 Tom Paciorek 156
115 Vance Law 155
116 J.C. Martin 150
T117 Smead Jolley 149
T117 Carl Everett 149
T117 Ted Lyons 149
120 Bill Skowron 146
T121 Jim Morrison 145
T121 Dave Martinez 145
123 Mike Hershberger 142
T124 Sam Mele 141
T124 Tommie Agee 141
T124 Mike Squires 141
127 George Kell 140
T128 Thurman Tucker 139
T128 Brian Downing 139
T128 Jim Spencer 139
T128 Rudy Law 139
132 Nemo Leibold 138
133 Alan Bannister 137
134 Red Kress 136
135 Gus Zernial 135
T136 Moose Solters 131
T136 Earl Torgeson 131
T136 Steve Lyons 131
139 Bob Fothergill 130
T140 Cliff Watwood 127
T140 Floyd Baker 127
142 Amos Strunk 124
T143 Daryl Boston 123
T143 Bubba Phillips 123
T145 Bill Hunnefield 122
T145 Buddy Bradford 122
T147 Rick Reichardt 121
T147 Dave Nicholson 121
T147 John Romano 121
T150 Greg Norton 118
T150 Duane Josephson 118
152 Julio Cruz 117
T153 Walt Williams 116
T153 Tony Bernazard 116
T153 John Kerr 116
T156 Sammy Sosa 113
T156 Eric McNair 113
T156 Ernie Johnson 113
159 Joe Cunningham 111
T160 Craig Grebeck 110
T160 Ed Hahn 110
T162 Tim Hulett 109
T162 Claudell Washington 109
T162 Roy Schalk 109
T165 Guy Curtright 108
T165 Joey Cora 108
T167 Tony Piet 107
T167 Mike Andrews 107
T169 Dixie Walker 106
T169 Ed McFarland 106
T171 Evar Swanson 105
T171 Cam Carreon 105
T171 Lu Blue 105
T174 Ferris Fain 103
T174 Oscar Gamble 103
T176 Richie Zisk 101
T176 Hal Trosky 101
T176 Danny Tartabull 101
179 Mike Cameron 100
Bernie Williams holds the record for most career postseason RBIs with 80.
Career and Single Season RBI LeadersHank Wilson of the Chicago Cubs holds the major League record for RBIs in a single season with 191 hit in 1930. New York Yankees, Lou Gehrig holds the American League record for RBIs in a single season with 184 in 1931. Hank Aaron holds the Major League record for career RBIs with 2,297 and the National League record with 2,202. Babe Ruth is second in career RBIs with 2,218, and hold the American League career RBI record with 2,201.
Red Ruffing. Hall of Famer Red Ruffing played 22 seasons with the Boston Red Sox, New York Yankees, and Chicago White Sox between 1924-1942 and 1945-1947. He had 273 career RBIs and a batting average of .269 with 98 doubles (also an MLB record for pitchers), 13 triples, and 36 home runs.
Ted Williams had a career batting average of .344, 521 home runs and 1,839 RBIs
Lou Gehrig had 1,995 RBIs during his career.
Hank Wilson holds the record for most RBIs in a single season with 191, set in 1930.
Bernie Williams has the most career postseason RBIs with 80.
Hank Aaron holds the MLB records for the most career runs batted in (RBI) (2,297), extra base hits (1,477), and total bases (6,856).
Father Bob Boone had 4 career WS RBIs and son Aaron Boone had 2 career WS RBIs. Father Julian Javier had 7 career WS RBIs and son Stan Javier had 2 career WS RBIs.
Mickey Mantle ended his career with 1,509 RBIs.
Roberto Clemente had 240 career home runs.
Click on the 'MLB Top 50 Lifetime RBIs' link on this page to see MLB's top 50 in career RBIs.