No. Since 1920, Alabama has only played 1 game at a Big 10 school, losing to Wisconsin in 1928. Alabama has won three games in State College against Penn State (1981, 1987, 1989) but all came before Penn State began playing football in the Big 10 in 1993.
Alabama
South Carolina last beat Alabama on October 9, 2010, during a regular-season college football game. The Gamecocks won 35-21, marking their first victory over the Crimson Tide in the history of their football program. This upset was significant, as Alabama was ranked No. 1 at the time. The win was celebrated as a major milestone for South Carolina football.
2005 but it doesn't count because they didn't beat an SEC team for the championship.
Gene stallings
University of Florida
Peyton Manning never played against the University of Alabama in college as he played for the University of Tennessee from 1994 to 1997. However, during his NFL career, Manning faced teams with Alabama players on their rosters but did not have any direct matchups against Alabama itself. His college rivalry with Alabama was marked by intense games, but he never secured a victory against them during his time at Tennessee.
On November 23rd, Alabama beat Auburn 24-23.
Ncaaf
On November 11, 1892, Alabama beat Birmingham High School 56-0.
Clemson is 3-12 against Alabama alltime.
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