no
You can have as many pinch runners as necessary. Of course, there are only 25 active players in the roster. In the American League, 10 of those players are already started in the game, leaving 15 players. Technically you could use 15 pinch runners if you really wanted to. Once a player is removed from the game, he cannot come back.
27
Lenny Harris
Texas Rangers
In MLB, it is a balk.
A defensive substitution or carry over of a pinch hitter.
Lenny Harris. Harris, who played between 1988-2005, holds the MLB record for pinch hits with 212.
MLB player Curtis Granderson throws right.
MLB player Adam LaRoche bats left.
MLB player Aaron Loup throws left.
MLB player Jose Ramirez can bat right or left (i.e. he is a switch hitter).