The NFL football is known as "The Duke". Not all college football teams use the same kind of football. The one that I am familiar playing with is the GST and it is more round and a little bit wider than an NFL football and the tips of the ball are not as pointed.
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They are both huge sports with a rabid fan base. When it comes to television ratings though nothing beats the NFL. They dominate the viewship market year after year in just about everything that gets thrown up against it.
If you are talking about the ball, the answer is NO, the official NFL ball is more narrow than the ball used in the NCAA.
If you are taking about popularity, then NFL is more widely followed because it is advertised much more. However, there are many more NCAA football teams than there are in the NFL because the skill level in college is much lower, allowing for more participants.
All footballs that are high school, college, and NFL level are the same. There is no physical difference besides the look of the ball.