On a Major League (MLB) roster, each team is allowed 25 "active" players on their rosters from the beginning of the season in March until the end of August. On September 1st, rosters are expanded to 40 players for the remainder of the regular season, typically lasting until the first week in October, at which time rosters are contracted back down to 25 players for those teams that have qualified for the postseason. So, from the beginning of the season until the last day in August teams have either 15 or 16 reserve players available to them (as American League teams utilize the designated hitter effectively producing 10 starters per game, whereas National League teams do not utilize the designated hitter), expanding to 30 or 31 reserve players (American League and National League respectively) from September 1st until the end of the regular season, contracting again to 15 (AL) or 16 (NL) for the duration of the playoffs. Although, not all "reserve" players are considered available for any given game as "starting" pitchers (of which, each team typically retains 5 for the regular season and 3 for the postseason) have "scheduled" starts and are not typically considered available for every game, atypical situations (playoff/important games, pure necessity) excluded.
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If your asking how many people normally play for one team its normally twelve to thirteen. The biggest I've seen a team is fourteen.