Babe Ruth died at age 53 on August 16, 1948 at Memorial Hospital in New York City of throat cancer, which he fought for 2 years.
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Ruth suffered from nasopharyngeal carcinoma (NPCA), a relatively rare tumor located in the back of the nose near the eustachian tube. (Wikipedia)
Babe Ruth died of cancer of the throat at Cancer Memorial Hospital in New York City on Aug. 16th, 1948.