Yes, the Pittsburgh Steelers (AFC) in 2005 and Green Bay Packers (NFC) in 2010.
Both were second wild-card teams (6th seed).
No two 6 seeds have ever faced each other in the Super Bowl.
Pittsburgh steelers
For the 2005 playoffs, the Steelers went in as the sixth seed. They won Super Bowl XL after winning in Cincinnati, Indianapolis and Denver.
17 teams won the super bowl that was the 1st seed
Since the NFL expanded its playoff field to six teams from each conference in 1990, the 2005 Pittsburgh Steelers and the 2010 Green Bay Packers have been the only No. 6 seeds to win the Super Bowl.
Super Bowl XXV (1990 season) through Super Bowl XLIII (2008 season): 1) Super Bowl XLII: AFC #1 seed New England Patriots lost to NFC #5 seed New York Giants. 2) Super Bowl XLI: NFC #1 seed Chicago Bears lost to AFC #3 seed Indianapolis Colts. 3) Super Bowl XL: NFC #1 seed Seattle Seahawks lost to AFC #6 seed Pittsburgh Steelers. 4) Super Bowl XXXIX: NFC #1 seed Philadelphia Eagles lost to AFC #2 seed New England Patriots. 5) Super Bowl XXXVIII: AFC #1 seed New England Patriots defeated NFC #3 seed Carolina Panthers. 6) Super Bowl XXXVII: AFC #1 seed Oakland Raiders lost to NFC #2 seed Tampa Bay Buccaneers. 7) Super Bowl XXXVI: NFC #1 seed St. Louis Rams lost to AFC #2 seed New England Patriots. 8) Super Bowl XXXV: NFC #1 seed New York Giants lost to AFC #4 seed Baltimore Ravens. 9) Super Bowl XXXIV: NFL #1 seed St. Louis Rams defeated AFC #4 seed Tennessee Titans. 10) Super Bowl XXXIII: AFC #1 seed Denver Broncos defeated NFC #2 seed Atlanta Falcons. 11) Super Bowl XXXI: NFC #1 seed Green Bay Packers defeated AFC #2 seed New England Patriots. 12) Super Bowl XXX: NFC #1 seed Dallas Cowboys defeated AFC #2 seed Pittsburgh Steelers. 13) Super Bowl XXIX: NFC #1 seed San Francisco 49ers defeated AFC #2 seed San Diego Chargers. 14) Super Bowl XXVIII: NFC #1 seed Dallas Cowboys defeated AFC #1 seed Buffalo Bills. 15) Super Bowl XXVI: NFC #1 seed Washington Redskins defeated AFC #1 seed Buffalo Bills. 16) Super Bowl XXV: AFC #1 seed Buffalo Bills lost to NFC #2 seed New York Giants.
Most recently the 10-6 Green Bay Packers as a 6th seed went to the Super Bowl in 2011 and beat the Pittsburgh Steelers.
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Pittsburgh Steelers
2005 Pittsburgh Steelers that defeated the Seattle Seahawks in Super Bowl XL.