The First regular season game played at Comiskey Park was on July 1, 1910. The park was built on a former city dump that Comiskey bought in 1909 to replace the wooden South Side Park. The first-ever All-Star Game was held there in 1933. The last game was played in 1990, and Comiskey Park was demolished in 1991.
At Normal Park and in 1922 they began playing at Comiskey Park.
Fritz Ackley debuted on September 21, 1963, playing for the Chicago White Sox at Comiskey Park; he played his final game on May 9, 1964, playing for the Chicago White Sox at Comiskey Park.
Herb Adams debuted on September 17, 1948, playing for the Chicago White Sox at Comiskey Park; he played his final game on August 30, 1950, playing for the Chicago White Sox at Comiskey Park.
Maurice Archdeacon debuted on September 17, 1923, playing for the Chicago White Sox at Comiskey Park; he played his final game on May 29, 1925, playing for the Chicago White Sox at Comiskey Park.
Francisco Barrios debuted on August 18, 1974, playing for the Chicago White Sox at Comiskey Park; he played his final game on June 3, 1981, playing for the Chicago White Sox at Comiskey Park.
Dennis Berran debuted on August 11, 1912, playing for the Chicago White Sox at Comiskey Park; he played his final game on August 11, 1912, playing for the Chicago White Sox at Comiskey Park.
Charlie Biggs debuted on September 3, 1932, playing for the Chicago White Sox at Comiskey Park; he played his final game on September 24, 1932, playing for the Chicago White Sox at Comiskey Park.
Emmett Bowles debuted on September 12, 1922, playing for the Chicago White Sox at Comiskey Park; he played his final game on September 12, 1922, playing for the Chicago White Sox at Comiskey Park.
Jerry Byrne debuted on August 31, 1929, playing for the Chicago White Sox at Comiskey Park; he played his final game on October 5, 1929, playing for the Chicago White Sox at Comiskey Park.
Joe Chamberlain debuted on April 17, 1934, playing for the Chicago White Sox at Comiskey Park; he played his final game on July 8, 1934, playing for the Chicago White Sox at Comiskey Park.
Ernie Cox debuted on May 5, 1922, playing for the Chicago White Sox at Comiskey Park; he played his final game on May 5, 1922, playing for the Chicago White Sox at Comiskey Park.
Wally Dashiell debuted on April 20, 1924, playing for the Chicago White Sox at Comiskey Park; he played his final game on April 20, 1924, playing for the Chicago White Sox at Comiskey Park.