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Yes ... Lou started feeling the effects of his illness in the 1938 season. He began to have back pains, his running was slower, he looked uncoordinated at times, and he was occasionally short of breath. Lou, as any proud man would, dismissed these things but, in reality, it was the onset of the ALS disease that would take his life. Lou Gehrig had played in 15 regular seasons. He was only second to teammate Babe Ruth in fame and Baseball name greats.

During spring training in 1939, his condition worsened to the point that he admitted how bad he was feeling. After 8 regular season games, he took himself out of the lineup never to return.

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