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If you mean for one game the largest margin of victory has to be a game I saw in 1957 when the Reds beat the Cubs 22-2 in Crosley Field. Every starter (including the pitcher Hal Jeffcoat) had a home run except for Frank Robinson.

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14y ago

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Cards came out on top this year with a winning record against the Reds (8-7).

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12y ago
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Q: Best record against Cincinnati Reds
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