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Depends on the skill of the shooter,the type of 22 rifle used and the type of ammo used in the rifle.

Generally a standard sub sonic 22LR 40gr SP round fired from a Rugger 10/22 rifle has an effective kill range of 50-75 yards.

A hyper sonic 22LR 40gr SP round fired from a ruger 10/22 has an effective kill range of 80-100 yards however at 100 yards the round drops upto 4 inches from the point of aim..

This however changes depending on the type of rifle used such as using a 22 magnum rifle which uses a longer cartrige and a higher powder charge.

The 22 magnum high velocity 40gr SP round fired from a Winchester 22 magnum rifle has an effective kill range of 120 -150 yards with a drop of 5-6 inches from point of aim.

Since the 22 is a rather small caliber to use on coyotes a head shot or heart shot would be more effective if shooting at ranges over 75 yards since coyotes can run almost a mile when a lung shot is made.

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