Drag car:
The world record for a 1/4 mile standing start pass is 4.428 seconds with a speed of 336.15 miles per hour (540.98 km/h).
Space Transportation System (STS) otherwise known as NASA's space shuttles such as the Challenger and Columbia:
Speed: 7,743 m/s (27,870 km/h; 17,320 mph)
It is often related that Top Fuel dragsters are the fastest accelerating vehicles on Earth even faster than the acceleration of a STS. The top speed however of these two vehicles are polar opposites.
Dragster world record top speed of 336.15mph
STS can reach speeds of 17,320 (yes 17,320) mph
So I guess if you raced a dragster against a space shuttle in a quarter mile, the dragster would win that race. As to which is "faster?" I'd say 17,000mph takes the cake.
http://en.wikipedia.org/wiki/Drag_racing
http://en.wikipedia.org/wiki/Space_Shuttle#Re-entry_and_landing
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It depends what you define as "fastest". Dragsters, specifically the top fuel dragster can have up to 8000hp. They are, bar NOTHING the fastest ACCELERATING vehicle on the planet. But, things such as rockets will make a higher top speed.
If by Lambo you mean Lamborghini, than yes! Although some times Audis can win....