As of writing this answer, Serena Williams has won 23 Grand Slam singles titles, which is the most by any professional tennis player in the Open era (and puts her second all-time behind Margaret Court with 24). She is currently competing in the 2022 US Open tournament, where she is hoping to win her 24th title. Williams has said that she is planning to "evolve away" from tennis after this year's US Open.
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According to Wikipedia (refer to the link, below), as of April 6, 2009, Serena Williams has won 14 tennis championships.