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Most think of Mary I as the first woman ruler, but Lady Jane Grey was actually the first woman to be crowned queen of England, even if she was only on the throne for nine days, she was then executed, on demand of Mary I.
The author of the first published book of poems by an American was Phillis Wheatley.
The first woman Prime Minister was Sirimavo Bandaranaike of Sri Lanka. She was prime minister from from 21 July 1960 to 27 March 1965, from 29 May 1970 to 23 July 1977 and from 14 November 1994 to 10 August 2000.
Rebecca Lee Crumpler became the first African American woman to receive an M.D. degree in the US when she graduated from the New England Female Medical College in 1864.
Elizabeth Blackwell, the first woman to receive a medical degree in the United States, immigrated to the US from Bristol, England.