Brett Favre - 366 interceptions in his career, regular season and playoffs.
In 2010, Eli Manning of the New York Giants threw the most interceptions with 25.
Through the 2008 season in the NFL, that is Brett Favre with 310 career interceptions.
Bret favre
Rich Gannon.
Brett farve for a fact has thrown the most touchdowns. But I'm not sure if he threw the most interceptions as well
Jay Cutler!
In 1955, Jim Finks threw 26 interceptions, that was the most by a Steelers quarterback in one season.
In 2010, Eli Manning of the New York Giants threw the most interceptions with 25.
Through the 2008 season in the NFL, that is Brett Favre with 310 career interceptions.
Jim hardy of the cardinals threw 8 interceptions in a game in the 1950's
Rich Gannon.
Bret favre
Through the 2008 season, that is John Hadl who threw 32 interceptions in the 1968 season.
In 1962, George Blanda, the Quarterback for the Houston Oilers, threw for 42 interceptions in a single season.
Brett farve for a fact has thrown the most touchdowns. But I'm not sure if he threw the most interceptions as well
Unknown, as the 2010 NFL season has not begun yet.
michael jordan