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In 1962, Willie Mays led Major League Baseball with 49 home runs. Harmon Killebrew was second, with 48.
Jimmie Foxx led the Major Leagues in 1933 with 48 home runs for Philadelphia.
Lou Gerhig 49.
No one (in the major leagues) hit home runs off Bob Feller in 1938.
Most Home Runs by a Second BasemanThe player with the most home runs by a second baseman in the National League was Jeff Kent with 351 home runs. Kent played 17 years in the Major Leagues, and had a total of 377 career home runs.The player with the most home runs by a second baseman in the American League was Joe Gordon with 246 home runs. Gordon played 11 years in the Major Leagues, and had a total of 253 career home runs.
No one ever has, at least in the major leagues, I think 15 or so have hit four.