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Through MLB games played on September 1, 2008 Barry Bonds hit the most career home runs. The top five home run leaders are: 1) Barry Bonds - 762

2) Hank Aaron - 756

3) Babe Ruth - 714

4) Willie Mays - 660

5) Sammy Sosa - 609

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โˆ™ 2008-09-01 22:05:22
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Q: Who hit the most home runs in American baseball?
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