Here's a list as of the start of the 2008 season:
CAREER
EARNED RUNS ER
1 Cy Young 2146
2 Phil Niekro 2012
3 Don Sutton 1914
4 Nolan Ryan 1911
5 Pud Galvin 1895
6 Gus Weyhing 1867
7 Steve Carlton 1864
8 Gaylord Perry 1846
9 Red Ruffing 1833
10 Bert Blyleven 1830
11 Warren Spahn 1798
12 Early Wynn 1796
13 Robin Roberts 1774
14 Tommy John 1749
15 Jim Kaat 1738
16 Earl Whitehill 1726
17 Roger Clemens 1707
18 Frank Tanana 1702
19 Ted Lyons 1696
20 Tom Glavine 1695
21 Ferguson Jenkins 1669
22 Greg Maddux 1665
23 Bobo Newsom 1664
24 Jamie Moyer 1662
25 Kid Nichols 1660
26 Jack Morris 1657
27 Sad Sam Jones 1656
28 Dennis Martinez 1643
29 Burleigh Grimes 1636
30 Charlie Hough 1582
31 David Wells 1578
32 Eppa Rixey 1572
33 Tony Mullane 1537
34 Tom Seaver 1521
35 Waite Hoyt 1500
36 Jerry Reuss 1483
37 Grover C Alexander 1476
38 Tim Keefe 1472
39 Kenny Rogers 1458
40 Adonis Terry 1456
41 Jack Powell 1450
T42 Mickey Welch 1447
T42 Mel Harder 1447
44 Bob Friend 1438
T45 Jack Quinn 1433
T45 Jerry Koosman 1433
47 Joe Niekro 1431
48 Red Faber 1430
49 Herb Pennock 1428
50 Walter Johnson 1424
51 John Clarkson 1417
52 Doyle Alexander 1406
53 Paul Derringer 1401
54 Mickey Lolich 1390
55 Bump Hadley 1389
T56 Bob Feller 1384
T56 George Uhle 1384
58 Mike Mussina 1383
T59 Randy Johnson 1381
T59 Mike Moore 1381
61 Chick Fraser 1371
T62 Chuck Finley 1366
T62 Jim Bunning 1366
64 Old Hoss Radbourn 1348
65 Mike Torrez 1340
66 Lefty Grove 1339
T67 Rick Reuschel 1330
T67 Ted Breitenstein 1330
69 Brickyard Kennedy 1329
70 Pink Hawley 1326
71 Bobby Witt 1324
72 Curt Simmons 1318
73 Mark Langston 1306
74 Mike Morgan 1303
75 Jesse Haines 1298
76 Tom Zachary 1295
77 Amos Rusie 1287
78 Danny Darwin 1286
T79 Willis Hudlin 1281
T79 Rick Wise 1281
81 Luis Tiant 1280
82 Bert Cunningham 1279
83 Dennis Eckersley 1278
84 Charlie Root 1274
T85 Claude Osteen 1268
T85 John Burkett 1268
T87 Tim Wakefield 1262
T87 Terry Mulholland 1262
T89 Bob Gibson 1258
T89 Jim Perry 1258
91 Freddie Fitzsimmons 1257
92 Al Orth 1256
T93 Curt Schilling 1253
T93 Jim Palmer 1253
95 Hooks Dauss 1250
96 Catfish Hunter 1248
T97 Lew Burdette 1246
T97 Clark Griffith 1246
99 Murry Dickson 1240
100 Larry Jackson 1233
101 Red Ehret 1229
102 Bill Hutchison 1228
103 Rube Walberg 1224
T104 Kid Carsey 1223
T104 Rick Sutcliffe 1223
106 John Smoltz 1221
T107 Vida Blue 1211
T107 Orel Hershiser 1211
109 Larry French 1206
110 Joe Bush 1205
111 Frank Dwyer 1204
T112 Milt Pappas 1203
T112 Scott Erickson 1203
114 Jim Slaton 1202
115 Billy Pierce 1201
T116 Jack Stivetts 1199
T116 Mike Flanagan 1199
118 Red Donahue 1194
T119 Bob Welch 1191
T119 Danny MacFayden 1191
121 Carl Hubbell 1188
T122 Lee Meadows 1185
T122 Kevin Brown 1185
124 Camilo Pascual 1183
T125 Steve Trachsel 1182
T125 Jim Clancy 1182
T127 Jouett Meekin 1177
T127 Wes Ferrell 1177
T129 Howard Ehmke 1175
T129 Frank Viola 1175
131 Eddie Plank 1174
132 Bob Forsch 1169
133 Vic Willis 1167
134 Guy Bush 1166
135 Dutch Leonard 1162
136 Dolf Luque 1161
137 George Mullin 1156
138 Jim McCormick 1155
T139 Jim Whitney 1154
T139 Dave Stewart 1154
T139 Fernando Valenzuela 1154
142 Brad Radke 1150
143 Pedro Astacio 1140
144 Bucky Walters 1139
145 Kevin Gross 1137
146 Christy Mathewson 1133
T147 Rube Marquard 1130
T147 Tim Belcher 1130
T147 Tom Candiotti 1130
150 Bill Lee 1127
T151 Silver King 1126
T151 Juan Marichal 1126
153 Don Drysdale 1124
154 Tommy Bridges 1122
T155 Charlie Buffinton 1120
T155 Bill Sherdel 1120
T157 Wilbur Cooper 1119
T157 Livan Hernandez 1119
T159 Bill Gullickson 1118
T159 Vern Law 1118
161 David Cone 1115
162 Ken Holtzman 1111
163 Steve Renko 1107
T164 Dave Stieb 1106
T164 Andy Benes 1106
T164 Bob Knepper 1106
167 Aaron Sele 1102
168 Kevin Tapani 1094
169 Scott Sanderson 1093
T170 Win Mercer 1091
T170 Dwight Gooden 1091
172 Paul Splittorff 1082
173 Jimmy Ring 1079
T174 Floyd Bannister 1078
T174 Kevin Appier 1078
T174 Jaime Navarro 1078
177 Andy Pettitte 1077
178 General Crowder 1072
T179 Dazzy Vance 1068
T179 Pedro Ramos 1068
T179 Esteban Loaiza 1068
182 Milt Gaston 1064
183 Jeff Suppan 1060
184 Jim Lonborg 1056
185 Joe Coleman 1055
186 Frank Killen 1054
T187 Doug Drabek 1052
T187 Bruce Hurst 1052
T187 Vern Kennedy 1052
T190 Ray Sadecki 1051
T190 Mark Baldwin 1051
192 Red Lucas 1048
193 Todd Stottlemyre 1042
T194 Rick Rhoden 1036
T194 Si Johnson 1036
T194 Sid Hudson 1036
197 Woody Williams 1031
T198 Bill Dinneen 1029
T198 Larry Benton 1029
200 Ned Garver 1027
201 Sadie McMahon 1026
202 Bob Lemon 1024
203 Jon Lieber 1022
204 Mike Caldwell 1020
205 Bob Buhl 1019
206 Jack Russell 1017
T207 Hal Newhouser 1016
T207 Ron Darling 1016
T207 Joe McGinnity 1016
T207 Clarence Mitchell 1016
211 Ray Burris 1015
212 Stan Bahnsen 1013
T213 Al Leiter 1010
T213 Jimmy Key 1010
T213 Woodie Fryman 1010
216 Virgil Trucks 1009
217 Bob Shawkey 1008
T218 Rudy May 1007
T218 Kid Gleason 1007
220 Eddie Rommel 1006
221 Claude Passeau 1003
222 Steve Rogers 1001
223 Elton Chamberlin 999
224 Joe Nuxhall 998
225 Bill Dietrich 997
T226 Burt Hooton 996
T226 Pat Hentgen 996
228 Tommy Thomas 995
229 Darryl Kile 992
230 Stan Coveleski 990
231 Mike McCormick 986
232 Mudcat Grant 985
233 Lon Warneke 984
234 Bob Smith 983
235 Dave McNally 982
236 Javier Vazquez 981
237 Charles Nagy 980
T238 Carl Mays 979
T238 Mike Cuellar 979
T238 Dizzy Trout 979
241 Mark Gubicza 978
T242 Syl Johnson 977
T242 Bob Rush 977
T244 Charlie Getzien 976
T244 Jack Taylor 976
246 Ed Brandt 974
247 Dick Ruthven 970
248 Whitey Ford 967
249 George Blaeholder 966
250 Wilbur Wood 965
T251 Elden Auker 964
T251 Art Nehf 964
253 Herm Wehmeier 961
254 Harry Staley 959
255 Greg Swindell 957
256 Schoolboy Rowe 955
257 Ron Reed 953
T258 Bret Saberhagen 952
T258 Charlie Leibrandt 952
T260 Mike Krukow 949
T260 Jack Billingham 949
T260 Scott McGregor 949
T263 Guy Hecker 944
T263 Ed Whitson 944
265 Ad Gumbert 942
T266 Urban Shocker 941
T266 Ray Benge 941
268 Matt Kilroy 939
269 John Candelaria 935
270 Red Ames 934
271 George Earnshaw 933
272 Walt Terrell 931
T273 Lefty Gomez 929
T273 Jeff Fassero 929
275 Stump Wiedman 928
276 Johnny Klippstein 927
277 Hal Schumacher 926
278 Johnny Podres 925
279 Don Cardwell 924
T280 Danny Jackson 923
T280 Hideo Nomo 923
282 Thornton Lee 921
283 Bill Doak 920
284 Jesse Barnes 918
T285 Jose Lima 917
T285 Fritz Ostermueller 917
T287 Chuck Stobbs 916
T287 Mike Hampton 916
T289 Babe Adams 915
T289 Allie Reynolds 915
291 Milt Wilcox 913
T292 Kirk Rueter 911
T292 Dan Petry 911
294 Bobby Mathews 910
295 Pete Donohue 909
T296 Sam Gray 906
T296 Tom Gordon 906
T296 Alex Kellner 906
299 Long Tom Hughes 905
300 Harvey Haddix 901
301 Bartolo Colon 899
T302 Dennis Leonard 898
T302 Mike Witt 898
T302 Jeff Weaver 898
305 Mike Boddicker 897
306 Will White 896
307 Mark Gardner 894
308 Rick Honeycutt 893
T309 Denny Neagle 891
T309 Bob Purkey 891
T309 Ken Hill 891
T309 Bob Caruthers 891
T309 Jack Fisher 891
314 Dick Ellsworth 890
T315 Chris Short 886
T315 Dave Burba 886
T315 Wild Bill Donovan 886
318 Denny Galehouse 885
T319 Nig Cuppy 884
T319 Curt Davis 884
321 Hal Carlson 883
T322 Dave Roberts 882
T322 Harry Gumbert 882
324 Sam McDowell 879
325 Mel Stottlemyre 878
326 Bud Black 876
T327 Joe Dobson 874
T327 Ron Guidry 874
329 Rich Dotson 872
330 Ed Lopat 869
331 Eric Milton 868
332 Jason Schmidt 867
T333 Ron Kline 866
T333 Rick Mahler 866
Here's a list as of the start of the 2008 season:
SEASON
EARNED RUNS YEAR ER
1 John Coleman 1883 291
2 Ted Breitenstein 1894 238
3 Red Donahue 1897 237
4 Al Mays 1887 232
5 Kid Carsey 1891 230
6 Gus Weyhing 1887 221
7 Henry Porter 1888 219
T8 Tony Mullane 1886 218
T8 Matt Kilroy 1886 218
10 Ed Seward 1887 216
T11 Kid Nichols 1894 215
T11 Old Hoss Radbourn 1887 215
T13 Toad Ramsey 1887 214
T13 Pink Hawley 1894 214
T13 Stump Wiedman 1886 214
16 George Cobb 1892 213
17 Ted Breitenstein 1895 212
18 Billy Crowell 1887 211
19 Phenomenal Smith 1887 207
T20 Mark Baldwin 1889 206
T20 Fleury Sullivan 1884 206
22 Bill Hart 1897 205
23 Ed Beatin 1890 202
T24 Frank Mountain 1883 201
T24 Matt Kilroy 1887 201
26 Bert Cunningham 1890 200
27 Larry McKeon 1884 199
T28 Red Ehret 1894 198
T28 Pud Galvin 1883 198
T30 Brickyard Kennedy 1894 197
T30 Park Swartzel 1889 197
T32 Egyptian Healy 1887 196
T32 Scott Stratton 1893 196
T32 Frank Dwyer 1894 196
T32 Jim Whitney 1886 196
36 Kid Gleason 1893 195
37 Red Ehret 1889 194
38 Tom Parrott 1894 192
T39 Bill Hart 1896 191
T39 Jack Taylor 1896 191
T39 Bill Hutchison 1892 191
T39 George Hemming 1893 191
T39 Hardie Henderson 1885 191
T44 Jack Lynch 1886 190
T44 Elton Chamberlin 1891 190
46 Chick Fraser 1896 189
T47 Adonis Terry 1884 188
T47 Jersey Bakely 1884 188
T47 John Clarkson 1889 188
T50 Bill Hutchison 1894 187
T50 Kid Carsey 1895 187
T50 Bill Carrick 1899 187
T53 George Haddock 1890 186
T53 Bobo Newsom 1938 186
55 Sadie McMahon 1890 185
T56 Mark Baldwin 1890 184
T56 Bill Hutchison 1893 184
T56 Jack Stivetts 1894 184
T59 Henry Gruber 1890 182
T59 Gus Weyhing 1893 182
T61 Ed Stein 1894 181
T61 Bill Hutchison 1890 181
T61 Gus Weyhing 1898 181
T61 Tony Mullane 1893 181
T61 Bob Barr 1884 181
66 Ad Gumbert 1894 180
T67 John Ewing 1889 179
T67 Cy Young 1894 179
T67 Hardie Henderson 1883 179
T67 John Clarkson 1887 179
71 Bob Barr 1890 178
T72 Charlie Getzien 1889 176
T72 Jersey Bakely 1888 176
T74 Al Maul 1893 175
T74 Bill Hutchison 1891 175
T74 Duke Esper 1893 175
T77 Lee Richmond 1881 174
T77 Al Atkinson 1886 174
T79 Amos Rusie 1893 173
T79 Mike Morrison 1887 173
T81 Jack Taylor 1898 172
T81 Gus Weyhing 1894 172
T81 Snake Wiltse 1902 172
T81 Sam Weaver 1883 172
T81 Red Donahue 1896 172
T86 Bert Cunningham 1888 171
T86 Lee Richmond 1882 171
T86 Kid Carsey 1894 171
T89 Amos Rusie 1892 170
T89 Mark Baldwin 1892 170
T89 WildBill Widner 1889 170
T89 Jim Hughey 1899 170
T89 Kid Carsey 1893 170
T89 Old Hoss Radbourn 1886 170
T89 Ed Crane 1890 170
T96 Frank Killen 1892 169
T96 John Keefe 1890 169
T96 Gus Weyhing 1899 169
T96 Ted Breitenstein 1896 169
T100 Win Mercer 1896 168
T100 Jouett Meekin 1894 168
T100 Frank Killen 1893 168
T100 Jock Menefee 1894 168
T100 Will White 1884 168
T100 Sadie McMahon 1893 168
T106 Jack Taylor 1895 167
T106 Frank Killen 1897 167
T106 Guy Hecker 1883 167
T109 Adonis Terry 1895 166
T109 Pink Hawley 1897 166
T109 Kid Nichols 1893 166
T109 Dan Casey 1890 166
T109 Dad Clarke 1896 166
T109 Mickey Welch 1886 166
T109 Frank Dwyer 1891 166
T109 Tim Keefe 1883 166
T117 Dad Clarkson 1894 165
T117 Henry Boyle 1889 165
T117 Pud Galvin 1885 165
T117 Tim Keefe 1887 165
T121 Charlie Ferguson 1884 164
T121 Frank Killen 1896 164
T121 Bobby Mathews 1876 164
T121 Jack Stivetts 1890 164
T121 Harry Staley 1889 164
T121 Silver King 1887 164
T127 Amos Rusie 1895 163
T127 Kid Gleason 1891 163
T129 Frank Foreman 1889 162
T129 Mickey Welch 1880 162
T129 Dickie Kerr 1921 162
T129 Jersey Bakely 1890 162
T133 Henry Porter 1886 161
T133 George Hemming 1894 161
T133 Pud Galvin 1887 161
T136 Nig Cuppy 1894 160
T136 Toad Ramsey 1886 160
T136 Tom Parrott 1895 160
T136 Henry Gruber 1891 160
T136 Stump Wiedman 1887 160
T136 Silver King 1889 160
T136 John Harkins 1884 160
T136 Darby O'Brien 1889 160
T144 Henry Porter 1887 159
T144 Bobby Mathews 1884 159
T144 Gus Weyhing 1891 159
T144 Tony Mullane 1884 159
T144 Brickyard Kennedy 1895 159
T149 Stump Wiedman 1883 158
T149 Cy Young 1893 158
T149 Pud Galvin 1889 158
T149 Fred Klobedanz 1897 158
T149 Harry Staley 1894 158
T149 Brickyard Kennedy 1893 158
T155 Pink Hawley 1895 157
T155 Lee Viau 1889 157
T155 Pud Galvin 1882 157
T155 Jim McCormick 1882 157
T155 Sadie McMahon 1891 157
T160 Amos Rusie 1890 156
T160 Jack Knott 1936 156
T160 Gus Weyhing 1890 156
T163 Bill Sweeney 1884 155
T163 Bob Caruthers 1889 155
T163 Red Ehret 1895 155
T163 Mickey Welch 1884 155
T163 Guy Bush 1930 155
T163 Willie McGill 1893 155
T163 Phil Knell 1894 155
T170 Win Mercer 1895 154
T170 Ray Kremer 1930 154
T170 Clark Griffith 1895 154
T170 Mark Baldwin 1893 154
T170 Jim McCormick 1887 154
T170 George Bradley 1879 154
T170 Hank O'Day 1890 154
T170 Ed Crane 1892 154
T178 Wes Ferrell 1937 153
T178 Bill Hill 1896 153
T178 Bill Hutchison 1895 153
T178 Danny Friend 1896 153
T178 Lev Shreve 1888 153
T178 Sam Kimber 1884 153
T178 Tony Mullane 1891 153
T178 Elton Chamberlin 1892 153
T186 Pat Caraway 1931 152
T186 Willie Sudhoff 1898 152
T186 Charlie Getzien 1887 152
T186 George Pechiney 1886 152
T186 Harry McCormick 1879 152
T186 Ed Morris 1887 152
T186 Ed Morris 1885 152
T186 Jack Lynch 1885 152
T186 Matt Kilroy 1889 152
T186 Jim Whitney 1881 152
T186 Tim Keefe 1886 152
T197 Bert Cunningham 1889 151
T197 Dan Daub 1894 151
T197 Ed Morris 1886 151
T197 Joe McGinnity 1901 151
T197 Silver King 1892 151
T202 Pink Hawley 1896 150
T202 Tom Lovett 1891 150
T202 Jim McCormick 1884 150
T202 Pud Galvin 1879 150
T202 Phil Knell 1891 150
T202 Will White 1879 150
T202 Jack Stivetts 1896 150
T202 Jack Stivetts 1895 150
T202 Tony Mullane 1887 150
T202 George Uhle 1923 150
T202 Brickyard Kennedy 1896 150
T202 Harry Staley 1893 150
T202 Mike Sullivan 1894 150
T215 Bump Hadley 1932 149
T215 Jack Taylor 1897 149
T215 Henry Porter 1885 149
T215 Cy Young 1896 149
T215 Gus Weyhing 1895 149
T215 Pete Conway 1886 149
T215 Denny Driscoll 1883 149
T215 Brickyard Kennedy 1897 149
T223 Jack Taylor 1899 148
T223 Kid Gleason 1890 148
T223 Kid Gleason 1892 148
T223 John Clarkson 1888 148
T223 Phil Niekro 1977 148
T228 Jack Lynch 1884 147
T228 Al Atkinson 1884 147
T228 Gus Weyhing 1889 147
T228 Robin Roberts 1956 147
T228 Jim McCormick 1879 147
T228 Ed Cushman 1890 147
T228 Bobo Newsom 1937 147
T228 Ted Breitenstein 1892 147
T236 Chick Fraser 1898 146
T236 George Earnshaw 1930 146
T236 Jack Powell 1899 146
T236 Sam Gray 1931 146
T236 Elmer Smith 1887 146
T236 Billy Serad 1884 146
T236 Bert Inks 1895 146
T236 Jack Wadsworth 1894 146
T236 Dave Foutz 1887 146
T236 Ed Cushman 1887 146
T236 Jim Whitney 1885 146
T236 Tom Vickery 1890 146
T236 Tommy Bond 1880 146
T236 Duke Esper 1894 146
T236 Jack Neagle 1883 146
T236 John Clarkson 1893 146
T252 Pedro Astacio 1998 145
T252 Herm Wehmeier 1950 145
T252 Al Orth 1897 145
T252 Bill Phillips 1901 145
T252 Jose Lima 2000 145
T252 Bill Hoffer 1897 145
T252 Harry Byrd 1953 145
T252 Ben Sanders 1890 145
T252 George Bradley 1877 145
T252 Jim Whitney 1887 145
T252 Ad Gumbert 1892 145
T252 Tim Keefe 1881 145
T264 Nels Potter 1939 144
T264 Kid Nichols 1895 144
T264 Jimmie DeShong 1937 144
T264 Matt Kilroy 1888 144
T264 Harley Payne 1897 144
T264 Old Hoss Radbourn 1883 144
T270 Toad Ramsey 1890 143
T270 Frank Foreman 1891 143
T270 Willie Sudhoff 1899 143
T270 Al Orth 1902 143
T270 Kid Nichols 1892 143
T270 Clark Griffith 1894 143
T270 Ray Benge 1930 143
T270 Jim McCormick 1881 143
T270 Dupee Shaw 1886 143
T270 Rube Walberg 1932 143
T270 John Clarkson 1891 143
T270 Sadie McMahon 1892 143
T270 Leo Sweetland 1930 143
T270 Billy Rhines 1895 143
T284 Jack Powell 1900 142
T284 Jouett Meekin 1896 142
T284 Mickey Lolich 1974 142
T284 Amos Rusie 1891 142
T284 Adonis Terry 1887 142
T284 Clark Griffith 1897 142
T284 George Keefe 1890 142
T291 Lee Richmond 1880 141
T291 Claude Passeau 1937 141
T291 Pete Dowling 1901 141
T291 Cy Young 1897 141
T291 Milt Gaston 1927 141
T291 Pud Galvin 1884 141
T291 Ed Seward 1889 141
T291 Vern Kennedy 1936 141
T291 Charlie Knepper 1899 141
T291 Bill Reidy 1901 141
T301 Monte Ward 1879 140
T301 Charlie Buffinton 1884 140
T301 Wes Ferrell 1936 140
T301 Chick Fraser 1901 140
T301 Jim Devlin 1877 140
T301 Jack Stivetts 1891 140
T301 Jack Stivetts 1892 140
T301 Darryl Kile 1999 140
T309 Egyptian Healy 1888 139
T309 Win Mercer 1894 139
T309 Nig Cuppy 1895 139
T309 Charlie Buffinton 1885 139
T309 Jack Russell 1930 139
T309 Ray Benge 1929 139
T309 Jim Bibby 1974 139
T309 Terry Larkin 1879 139
T309 Jack Stivetts 1893 139
T309 Gus Weyhing 1892 139
T309 Harry Staley 1890 139
T309 Dupee Shaw 1884 139
T309 Hank O'Day 1888 139
T309 John Clarkson 1890 139
T309 Bob Emslie 1884 139
T309 Bill Carrick 1902 139
T309 Elton Chamberlin 1889 139
T326 Burleigh Grimes 1925 138
T326 Bill Hart 1895 138
T326 Bert Cunningham 1899 138
T326 Wilbur Wood 1973 138
T326 Bump Hadley 1933 138
T326 Mike McDermott 1895 138
T326 Vern Kennedy 1940 138
T326 Gordon Rhodes 1936 138
T326 Pud Galvin 1880 138
T326 Ben Sanders 1889 138
T326 Larry Corcoran 1884 138
T326 Silver King 1890 138
Pitcher Jamie Moyer, who played in the major leagues until he was 49 years old in 2012, holds the record for most home runs yielded with 522. On June 27, 2010, as a member of the Philadelphia Phillies, he surpassed the record of the late Robin Roberts, who gave up 505 homers during his career.
Most Career Home Runs: Through October 22, 2016, Barry Bonds has the most career home runs with 762. Hank Aaron previously held the record with 755 home runs. Third on the career home run list is Babe Ruth with 714, and Alex Rodriguez, fourth with 696. Fifth on the list is Willie Mays with 660 home runs.
So far in the 2010 Major League Baseball season Kevin Millwood of the Baltimore Orioles has given up the most home runs with 20. There are three pitchers who have given up 19 home runs.
Warren SpahnWarren Spahn gave up 18 home runs to Willie Mays.
For a career that would be Hank Aaron with 755.
Jamie Moyer gave up 511 home runs in his career, more than any other MLB pitcher.
Barry Bonds has the most career home runs with 762.
Babe Ruth has the most career home runs as a Yankee with 659.
Tiger Woods
Mickey Mantle has the most career World Series home runs with 18.
Rafael Palmeiro with 569 career home runs.
Pitcher Jamie Moyer, who played in the major leagues until he was 49 years old in 2012, holds the record for most home runs yielded with 522. On June 27, 2010, as a member of the Philadelphia Phillies, he surpassed the record of the late Robin Roberts, who gave up 505 homers during his career.
=== === === ===
Most Career Home Runs: Through October 22, 2016, Barry Bonds has the most career home runs with 762. Hank Aaron previously held the record with 755 home runs. Third on the career home run list is Babe Ruth with 714, and Alex Rodriguez, fourth with 696. Fifth on the list is Willie Mays with 660 home runs.
Slugger Barry Bonds holds the record for the most home runs in a career. In the course of his career, he blasted 762 out of the park.
Brad Hodge with 2228 runs.
Barry Bonds holds the major league records for most home runs in a career (762) and most home runs in a season (73).