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1) David Ortiz in the first inning of the game on August 12, 2008 against the Texas Rangers.

2) Nomar Garciaparra in the third inning of the first game of a doubleheader against the Tampa Bay Devil Rays on July 23, 2002.

3) Ellis Burke in the fourth inning of the game against the Cleveland Indians on August 27, 1990.

4) Bill Regan in the fourth inning of the game against the Chicago White Sox on June 16, 1928. The second home run was an inside the park homer.

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Carl Yastrzemski.

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Q: Which Red Sox hit 2 home runs in an inning?
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