Ryan Howard debuted on September 1, 2004, playing for the Philadelphia Phillies at Citizens Bank Park; he played his final game on July 5, 2013, playing for the Philadelphia Phillies at Citizens Bank Park.
Ryan Wagner debuted on July 19, 2003, playing for the Cincinnati Reds at Great American Ball Park; he played his final game on May 6, 2007, playing for the Washington Nationals at R.F.K. Stadium.
Nolan Ryan debuted on September 11, 1966, playing for the New York Mets at Shea Stadium; he played his final game on September 22, 1993, playing for the Texas Rangers at Arlington Stadium.
Ryan Spilborghs debuted on July 16, 2005, playing for the Colorado Rockies at Coors Field; he played his final game on September 5, 2011, playing for the Colorado Rockies at Coors Field.
Perry Currin debuted on June 29, 1947 and played his final game on September 17, 1947.
Ryan Drese debuted on July 29, 2001 and played his final game on April 14, 2006.
Ryan Brasier debuted on May 2, 2013 and played his final game on September 27, 2013.
Ryan Christenson debuted on April 20, 1998, playing for the Oakland Athletics at Oakland Coliseum; he played his final game on September 28, 2003, playing for the Texas Rangers at The Ballpark at Arlington.
Ryan Cook debuted on July 20, 2011, playing for the Arizona Diamondbacks at Chase Field; he played his final game on September 29, 2013, playing for the Oakland Athletics at O.co Coliseum.
Perry Currin debuted on June 29, 1947 and played his final game on September 17, 1947.
Ryan Drese debuted on July 29, 2001 and played his final game on April 14, 2006.
Ryan Brasier debuted on May 2, 2013 and played his final game on September 27, 2013.
Ryan Adams debuted on May 20, 2011 and played his final game on September 19, 2011.
Ryan Bowen debuted on July 22, 1991 and played his final game on October 1, 1995.
Ryan Budde debuted on July 31, 2007 and played his final game on May 12, 2010.
Ryan Bukvich debuted on July 12, 2002 and played his final game on July 4, 2008.
Ryan Christenson debuted on April 20, 1998 and played his final game on September 28, 2003.
Ryan Church debuted on August 21, 2004 and played his final game on October 2, 2010.
Ryan Cook debuted on July 20, 2011 and played his final game on September 29, 2013.
Ryan Dempster debuted on May 23, 1998 and played his final game on September 29, 2013.
Ryan Doumit debuted on June 5, 2005 and played his final game on September 29, 2013.