Pedro Astacio debuted on July 3, 1992, playing for the Los Angeles Dodgers at Dodger Stadium; he played his final game on September 27, 2006, playing for the Washington Nationals at R.F.K. Stadium.
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Pedro Borbon debuted on April 9, 1969 and played his final game on May 25, 1980.
Pedro Dibut debuted on May 1, 1924 and played his final game on April 22, 1925.
Pedro Hernandez debuted on September 8, 1979, playing for the at ; he played his final game on July 11, 1982, playing for the Toronto Blue Jays at Exhibition Stadium.
Pedro Guerrero debuted on September 22, 1978, playing for the Los Angeles Dodgers at Dodger Stadium; he played his final game on October 4, 1992, playing for the St. Louis Cardinals at Busch Stadium II.
Pedro Strop debuted on August 28, 2009, playing for the Texas Rangers at Rangers Ballpark in Arlington; he played his final game on September 29, 2013, playing for the Chicago White Sox at U.S. Cellular Field.