Otis Stocksdale debuted on July 24, 1893, playing for the Washington Senators at Boundary Field; he played his final game on May 2, 1896, playing for the Baltimore Orioles at Union Park.
Otis Brannan debuted on April 11, 1928 and played his final game on October 5, 1929.
Otis Thornton debuted on July 6, 1973, playing for the Houston Astros at Astrodome; he played his final game on July 6, 1973, playing for the Houston Astros at Astrodome.
Harry Otis debuted on September 5, 1909, playing for the Cleveland Naps at League Park I; he played his final game on September 29, 1909, playing for the Cleveland Naps at League Park I.
Otis Lambeth debuted on July 16, 1916, playing for the Cleveland Indians at League Park II; he played his final game on April 24, 1918, playing for the Cleveland Indians at League Park II.
Bill Otis debuted on July 4, 1912, playing for the New York Highlanders at Hilltop Park; he played his final game on July 6, 1912, playing for the New York Highlanders at Hilltop Park.
Otis Brannan debuted on April 11, 1928 and played his final game on October 5, 1929.
Otis Clymer debuted on April 14, 1905 and played his final game on August 8, 1913.
Otis Davis debuted on April 22, 1946 and played his final game on April 22, 1946.
Otis Davis debuted on April 22, 1946, playing for the at ; he played his final game on April 22, 1946, playing for the at .
NFL player Otis Hudson played for Eastern Illinois.
Otis Thornton debuted on July 6, 1973, playing for the Houston Astros at Astrodome; he played his final game on July 6, 1973, playing for the Houston Astros at Astrodome.
Otis Miller debuted on April 17, 1927, playing for the St. Louis Browns at Sportsman's Park IV; he played his final game on April 29, 1932, playing for the at .
Harry Otis debuted on September 5, 1909, playing for the Cleveland Naps at League Park I; he played his final game on September 29, 1909, playing for the Cleveland Naps at League Park I.
Otis Lawry debuted on June 28, 1916, playing for the Philadelphia Athletics at Shibe Park; he played his final game on September 29, 1917, playing for the Philadelphia Athletics at Shibe Park.
Otis Lambeth debuted on July 16, 1916, playing for the Cleveland Indians at League Park II; he played his final game on April 24, 1918, playing for the Cleveland Indians at League Park II.
Bill Otis debuted on July 4, 1912, playing for the New York Highlanders at Hilltop Park; he played his final game on July 6, 1912, playing for the New York Highlanders at Hilltop Park.
Otis Clymer debuted on April 14, 1905, playing for the Pittsburgh Pirates at Exposition Park; he played his final game on August 8, 1913, playing for the Boston Braves at South End Grounds III.