Luke Appling debuted on September 10, 1930, playing for the Chicago White Sox at Comiskey Park; he played his final game on October 1, 1950, playing for the Chicago White Sox at Comiskey Park.
Luke Hughes debuted on April 28, 2010, playing for the Minnesota Twins at Target Field; he played his final game on April 29, 2012, playing for the Oakland Athletics at O.co Coliseum.
Lucas Luetge debuted on April 7, 2012, playing for the Seattle Mariners at Safeco Field; he played his final game on September 28, 2013, playing for the Seattle Mariners at Safeco Field.
Luke Easter debuted on August 11, 1949 and played his final game on May 4, 1954.
Matt Luke debuted on April 3, 1996, playing for the at ; he played his final game on September 30, 1999, playing for the Anaheim Angels at Edison International Field.
Dusty Hughes debuted on September 6, 2009, playing for the Kansas City Royals at Kauffman Stadium; he played his final game on May 27, 2011, playing for the Minnesota Twins at Target Field.
Luke Walker debuted on September 7, 1965, playing for the Pittsburgh Pirates at Forbes Field; he played his final game on October 1, 1974, playing for the Detroit Tigers at Tiger Stadium.
Bobby Hughes played in just one game at designated hitter for the Milwaukee Brewers in 1999 and did not start. , equivalent to 0 errors per game (estimate based on total games played in).
NFL player John Hughes played for Cincinnati.
NFL player Kofi Hughes played for Indiana.
Luke Easter debuted on August 11, 1949 and played his final game on May 4, 1954.
Luke Allen debuted on September 10, 2002 and played his final game on July 17, 2003.
Luke Appling debuted on September 10, 1930 and played his final game on October 1, 1950.
Luke Boone debuted on September 9, 1913 and played his final game on September 2, 1918.
Luke Carlin debuted on May 10, 2008 and played his final game on May 30, 2012.
NFL player Robert Hughes played for Notre Dame.
NFL player Kevin Hughes played for Southeastern Louisiana.
NFL player Montori Hughes played for Tennessee-Martin.
Luke Hughes played in 2 games at third base for the Minnesota Twins in 2010, starting in all of them. He played for a total of 48 outs, equivalent to 1.78 9-inning games. He made no putouts, had 4 assists, and committed no errors, equivalent to 0 errors per 9-inning game. He had one double play.
Keith Hughes debuted on May 19, 1987, playing for the at ; he played his final game on May 20, 1993, playing for the Cincinnati Reds at Riverfront Stadium.