Kyle McPherson debuted on August 20, 2012, playing for the Pittsburgh Pirates at PNC Park; he played his final game on September 29, 2012, playing for the Pittsburgh Pirates at PNC Park.
Kyle Abbott debuted on September 10, 1991 and played his final game on August 24, 1996.
Andy Kyle debuted on September 7, 1912, playing for the Cincinnati Reds at Crosley Field; he played his final game on October 6, 1912, playing for the Cincinnati Reds at Crosley Field.
Kyle Waldrop debuted on September 5, 2011, playing for the Minnesota Twins at Target Field; he played his final game on October 2, 2012, playing for the Minnesota Twins at Target Field.
Kyle Drabek debuted on September 15, 2010, playing for the Toronto Blue Jays at Rogers Centre; he played his final game on September 25, 2013, playing for the Toronto Blue Jays at Rogers Centre.
Kyle Lohse debuted on June 22, 2001, playing for the Minnesota Twins at Hubert H Humphrey Metrodome; he played his final game on September 25, 2013, playing for the Milwaukee Brewers at Miller Park.
Kyle Abbott debuted on September 10, 1991 and played his final game on August 24, 1996.
Kyle Blanks debuted on June 19, 2009 and played his final game on September 25, 2013.
Kyle Davies debuted on May 21, 2005 and played his final game on July 25, 2011.
Kyle Denney debuted on September 14, 2004 and played his final game on September 29, 2004.
Kyle Drabek debuted on September 15, 2010 and played his final game on September 25, 2013.
Kyle Farnsworth debuted on April 29, 1999 and played his final game on September 29, 2013.
John McPherson debuted on July 12, 1901, playing for the Philadelphia Athletics at Columbia Park; he played his final game on July 10, 1904, playing for the Philadelphia Phillies at Baker Bowl.
NBA player Kyle Anderson played for UCLA.
NBA player Kyle Lowry played for Villanova.
NBA player Kyle Singler played for Duke.
NFL player Kyle Arrington played for Hofstra.
NFL player Kyle Sebetic played for Dayton.