Juan Padilla debuted on July 16, 2004, playing for the New York Yankees at Yankee Stadium II; he played his final game on October 1, 2005, playing for the New York Mets at Shea Stadium.
Juan Perez debuted on September 7, 2006, playing for the Pittsburgh Pirates at PNC Park; he played his final game on August 9, 2013, playing for the Toronto Blue Jays at Rogers Centre.
Juan Delis debuted on April 16, 1955 and played his final game on September 18, 1955.
Juan Lara debuted on September 8, 2006, playing for the Cleveland Indians at Jacobs Field; he played his final game on September 6, 2007, playing for the Cleveland Indians at Jacobs Field.
Juan Nieves debuted on April 10, 1986, playing for the Milwaukee Brewers at County Stadium; he played his final game on October 2, 1988, playing for the Milwaukee Brewers at County Stadium.
Ponce, Mayaguez and San Juan
Juan Lagares debuted on April 23, 2013, playing for the New York Mets at Citi Field; he played his final game on September 29, 2013, playing for the New York Mets at Citi Field.
Juan Padilla played in 24 games at pitcher for the New York Mets in 2005, starting in none of them. He played for a total of 109 outs, equivalent to 4.04 9-inning games. He made one putout, had 6 assists, and committed no errors, equivalent to 0 errors per 9-inning game. He had one double play.
Juan Delis debuted on April 16, 1955 and played his final game on September 18, 1955.
Juan Abreu debuted on August 29, 2011 and played his final game on September 27, 2011.
Juan Acevedo debuted on April 30, 1995 and played his final game on August 5, 2003.
Juan Alvarez debuted on September 1, 1999 and played his final game on June 3, 2003.
Juan Bell debuted on September 6, 1989 and played his final game on August 25, 1995.
Juan Berenguer debuted on August 17, 1978 and played his final game on October 4, 1992.
Juan Bernhardt debuted on July 10, 1976 and played his final game on April 8, 1979.
Juan Bonilla debuted on April 9, 1981 and played his final game on October 3, 1987.
Juan Brito debuted on May 3, 2002 and played his final game on October 3, 2004.
Juan Castillo debuted on April 12, 1986 and played his final game on April 17, 1989.
Juan Castro debuted on September 2, 1995 and played his final game on June 4, 2011.