Frank Howard debuted on September 10, 1958, playing for the Los Angeles Dodgers at Los Angeles Memorial Coliseum; he played his final game on September 30, 1973, playing for the Detroit Tigers at Tiger Stadium.
Frank House debuted on July 21, 1950, playing for the Detroit Tigers at Briggs Stadium; he played his final game on September 25, 1961, playing for the Detroit Tigers at Tiger Stadium.
Frank Jude debuted on July 9, 1906, playing for the Cincinnati Reds at Palace of the Fans; he played his final game on October 7, 1906, playing for the Cincinnati Reds at Palace of the Fans.
Frank Abercrombie debuted on October 21, 1871 and played his final game on October 21, 1871.
Frank Allen debuted on April 24, 1912 and played his final game on September 19, 1917.
Frank Bahret debuted on April 17, 1884 and played his final game on April 22, 1884.
Frank Bowerman debuted on August 24, 1895 and played his final game on July 13, 1909.
Frank Brill debuted on June 23, 1884 and played his final game on August 8, 1884.
Frank Coggins debuted on September 10, 1967 and played his final game on July 30, 1972.
Frank Dupee debuted on August 24, 1901 and played his final game on August 24, 1901.
Frank Arellanes debuted on July 28, 1908 and played his final game on August 14, 1910.
Frank Baker debuted on July 27, 1969 and played his final game on September 29, 1971.
Frank Barberich debuted on September 17, 1907 and played his final game on June 16, 1910.
Frank Barnes debuted on April 18, 1929 and played his final game on September 26, 1930.
Frank Barrett debuted on October 1, 1939 and played his final game on September 15, 1950.
Frank Barron debuted on August 19, 1914 and played his final game on August 19, 1914.
Frank Bates debuted on October 7, 1898 and played his final game on September 9, 1899.
Frank Baumholtz debuted on April 15, 1947 and played his final game on May 26, 1957.
Frank Beck debuted on May 2, 1884 and played his final game on September 18, 1884.
Frank Bell debuted on July 7, 1885 and played his final game on July 31, 1885.