Francisco Barrios debuted on August 18, 1974, playing for the Chicago White Sox at Comiskey Park; he played his final game on June 3, 1981, playing for the Chicago White Sox at Comiskey Park.
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Manuel Barrios debuted on September 16, 1997 and played his final game on July 3, 1998.
Francisco Santos debuted on June 18, 2003, playing for the San Francisco Giants at PacBell Park; he played his final game on July 3, 2003, playing for the San Francisco Giants at PacBell Park.
Francisco Cruceta debuted on September 21, 2004, playing for the Cleveland Indians at Jacobs Field; he played his final game on June 2, 2008, playing for the Detroit Tigers at Comerica Park.
Francisco Cordero debuted on August 2, 1999, playing for the Detroit Tigers at Tiger Stadium; he played his final game on August 1, 2012, playing for the Houston Astros at Minute Maid Park.
Frank Francisco debuted on May 14, 2004, playing for the Texas Rangers at The Ballpark at Arlington; he played his final game on September 29, 2013, playing for the New York Mets at Citi Field.