Brian Looney debuted on September 26, 1993, playing for the Montreal Expos at Stade Olympique; he played his final game on June 8, 1995, playing for the Boston Red Sox at Fenway Park II.
Brian Buscher debuted on July 27, 2007 and played his final game on October 4, 2009.
Brian Daubach debuted on September 10, 1998 and played his final game on July 8, 2005.
Brian Esposito debuted on June 2, 2007 and played his final game on September 30, 2010.
Brian Bowles debuted on June 27, 2001 and played his final game on September 8, 2003.
Brian Greer debuted on September 13, 1977, playing for the at ; he played his final game on September 20, 1979, playing for the San Diego Padres at Jack Murphy Stadium.
NFL player Joe Looney played for Wake Forest.
Brian Buscher debuted on July 27, 2007 and played his final game on October 4, 2009.
Brian Daubach debuted on September 10, 1998 and played his final game on July 8, 2005.
Brian Esposito debuted on June 2, 2007 and played his final game on September 30, 2010.
Brian Bowles debuted on June 27, 2001 and played his final game on September 8, 2003.
Brian Allard debuted on August 8, 1979 and played his final game on June 10, 1981.
Brian Anderson debuted on September 10, 1993 and played his final game on May 8, 2005.
Brian Asselstine debuted on September 14, 1976 and played his final game on October 3, 1981.
Brian Banks debuted on September 9, 1996 and played his final game on September 28, 2003.
Brian Barber debuted on August 12, 1995 and played his final game on August 1, 1999.
Brian Barden debuted on April 3, 2007 and played his final game on July 2, 2010.
Brian Bark debuted on July 6, 1995 and played his final game on September 8, 1995.