The 1906 Chicago Cubs had the best winning percentage over the course of an entire season, going 116-36 (.764) In the modern era, (162 game schedule) the 2001 Seattle Mariners own the regular season crown. They went 116 and 46 (.716). Despite their record setting regular seasons, neither of these teams won the world series.
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As far as MLB goes, through the games played on July 24, 2008 that would be the New York Yankees who have a .561 all time winning percentage. Their all time record is 9439-7207. The team with the most all time wins is the Giants with 10,227. The Cubs are next with 10,045.
N.Y. Yankees : W-103 / L-59
By the winners of each division and one wildcard team from each league. Wildcard team faces the best record team in each league unless the team with the best record and the wildcard team are from the same division. In that case, the wildcard team plays the divisional winner with the next best record.
The Yankees 103-59 they have the best record in the bigs!!!!!!!!
the 1930 Philadelphia Phillies had a combined team ERA of 6.71. the team's overall record was 52-102. the 2nd highest team era was by the 1996 Detroit Tigers who had an ERA of 6.38 and a record of 53-109
St. Louis Blues