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The 1906 Chicago Cubs and the 2001 Seattle Mariners both won a record 116 games. The Cubs, however, set the mark in 152 games. The Mariners, paced by rookie phenom Ichiro Suzuki, accomplished the feat in 162 games.

The Cubs lost the 1906 World Series in six games to their crosstown rivals, the Chicago White Sox. The Mariners lost the American League Championship Series in five games to the New York Yankees.

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