The 1906 Chicago Cubs and the 2001 Seattle Mariners both won a record 116 games. The Cubs, however, set the mark in 152 games. The Mariners, paced by rookie phenom Ichiro Suzuki, accomplished the feat in 162 games.
The Cubs lost the 1906 World Series in six games to their crosstown rivals, the Chicago White Sox. The Mariners lost the American League Championship Series in five games to the New York Yankees.
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The most wins in a season before the schedule was increased to 162 games was by the 1906 Chicago Cubs who won 116 games. This is still the record for most wins in an MLB regular season. It was tied in 2001 by the Seattle Mariners.
The 1982 Atlanta Braves and the 1987 Milwaukee Brewers won thirteen games to open the season. http://mlb.com/video/play.jsp?content_id=20030503&c_id=mlb
Denny McLain, who won 16 straight road games in 1968.
The MLB record for fewest wins by a team in a season was set by the 1899 Cleveland Spiders. They won 20 games that season and lost 134. The 134 losses is also an MLB record for most losses by a team in a season.
The Cubs (1906) and Mariners (2001) who won 116 games in one season.