Cy Young had 316 career losses. He also had the most wins, complete games, innings pitched, and pretty much every other career record associated with longevity.
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Mel Stottlemyre has the most losses in Yankees history with 139.
Cy Young was a pitcher in the early years of Major League Baseball. He still holds many records including most career wins and most career losses.
Anthony Young: 27 Games, May 6, 1992 to July 24, 1993
The Major League Baseball pitcher with the most career wins and the fewest losses is Whitey Ford, who had a record of 236 wins and 106 losses during his career with the New York Yankees. Ford's win-loss percentage of .690 is the highest among pitchers with at least 200 career wins. Ford played from 1950 to 1967 and was known for his exceptional control and ability to pitch in pressure situations, earning him the nickname "The Chairman of the Board."
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