Through the 2008 season, that is 31 by Sid Luckman in 1947.
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Through the 2008 season in the NFL, that is Brett Favre with 310 career interceptions.
The quarterback that has the most interceptions is Brett Favre, he has 22 interceptions
Brett farve for a fact has thrown the most touchdowns. But I'm not sure if he threw the most interceptions as well
Season: Vinny Testaverde of the 1988 Tampa Bay Buccaneers with 35. Career: Brett Favre with 317 between 1991 and 15 games of the 2009 season.
There are three New York Giants who are tied for the dubious distinction of having thrown the most interceptions in a single season. This terrific trio each threw 25 interceptions in a single season. These players are:Eli Manning 2010 (25 int's in 16 games)Charlie Conerly 1953 (25 int's in 12 games)Frank Filchock 1946 (25 int's in 12 games)So far, thru 7 games in the 2013 NFL season, NY Giants signal caller Eli Manning has thrown 15 interceptions. If he continues this trend, Manning would be on pace to throw 33 interceptions, eclipsing his career high of 25 single season interceptions.