In the regular season, Bob Allison.
Allison hit the first home run in Twins regular season history in the 7th inning of their first ever regular season game (April 11, 1961) against the New York Yankees at Yankee Stadium.
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In 2011, the Minnesota Twins hit 103 home runs.
34000
Jim Thome (57)
On May 5, 1997, at Yankee Stadium, Derek Jeter hit his first home run against the Minnesota Twins. It was a 3 run homer, hit off of Rick Aguilera.
172 ... 9th most in the American League.